LPL and hypertriglyceridemia: Hypertriglyceridemia is related to decreased activity of the lipoprotein lipase (LPL) (16), which results in decreased clearance of triglyceride rich lipoproteins and of the hepatic lipase (HL) (17), which hydrolyzes High Density Lipoprotein (HDL) and is involved in the conversion of IDLs to LDL and of LDL to small dense LDL (sdLDL).