Moreover, transcriptional activity of the Mc2r gene may be upregulated by diverse transcription factors, like JDP2 (Jun dimerization protein 2) (46), FOXL2 (Forkhead box protein L2), or NR5A1 (steroidogenic factor 1) (47), which, in the context of Tc infection, may be disturbed. Here, MC2R is linked to infection.