HSP90B2P and neurodegenerative disease: For their role in regulating protein homeostasis, HSP expression has been proposed as a therapeutic target for the treatment of these neurodegenerative diseases (Carman et al., 2013; Kalmar et al., 2014; Schapira et al., 2014; Ciechanover and Kwon, 2017; Webster et al., 2017; Klaips et al., 2018).