After 12 weeks of intervention, Vs, Sr, and SRr in the DM model group were significantly lower than those in the normal control group (P < 0.05); Vs, Sr, and Sr in the FGF1 solution group, FGF1-nlip group, and FGF1-nlip+UTMD group were significantly higher than those in the model group (P < 0.05); those in the FGF1-nlip+UTMD group were higher than those in the other intervention groups (P < 0.05) (Table 2). Here, FGF1 is linked to diabetes mellitus.