SIRT2 and Parkinson disease: SIRT2 regulates microtubule function, cell cycle, oxidative stress, autophagy, and neuroinflammation, all of which are recognized as prominent processes in the pathogenesis of PD (Zhao et al., 2010b; Maxwell et al., 2011; de Oliveira et al., 2012; Liu et al., 2014; Kida and Goligorsky, 2016).