TLX3 and viral infectious disease: To restrict the viral infection to a particular cell population, we again used Tlx3-Cre mice, a layer 5-specific Cre-line; we injected Cre-dependent AAV expressing oTVB-H-tagBFP (AAV2/9-CAG-DIO-oTVB-H-tagBFP) to the V1 of Tlx3-Cre mice (Figure 3D).