Dey and colleagues (2010) found that intrastriatal transplantation of MSCs genetically altered to overexpress BDNF, which is reduced in HD patients,21 decreased the motor deficits and neuronal loss in YAC128 HD mice.20 We also transplanted MSCs derived from UC‐MSCs into the striata of R6/2 HD mice. Here, BDNF is linked to Huntington disease.