And finally, levels of 17β-HSD10–cypD complexes were significantly decreased (the drops to 85.6% in MCI-AD, to 83.9% in ADD and to 89.9% in FTLD) when compared to controls (a part of the results is presented also in Fig. 6, in addition, the insert in the top-right corner shows dependency of optical density on CSF volume). This evidence concerns the gene HSD17B10 and Alzheimer disease.