Shown by Kruskal Wallis test, tissues with stromal staining of OPN-N ( ≥ 1) had more often higher tumour cell expression of OPN-N (OPN-Clow/OPN-Nhigh and OPN-Chigh/OPN-Nhigh, p < 0.0001) while tissues with stromal OPN-C were equally distributed between the different categories of tumour cell expression. This evidence concerns the gene SPP1 and neoplasm.