Recently, Bolstad AI et al. investigated whether SNPs in the LTA gene clusters were correlated with primary Sjogren ‘s syndrome, and they found that LTA rs909253 and rs1800629 had significantly association with primary Sjogren’s syndrome, and the correlations were mainly due to anti-Ro/SSA and anti-La/SSB antibody-positive primary Sjogren’s syndrome26. This evidence concerns the gene SSB and Sjogren syndrome.