LTF and Sepsis: When ELFIN is combined with LIFT_ANZ and all other trials, a total of 5011 infants, the overall effect of lactoferrin is to reduce the relative risk of late onset sepsis to 0.82 (95% 0.74–0.92; P = 0.0004), with moderate heterogeneity (I2 = 0.58) and asymmetric funnel plot, consistent with small study effects (personal communication, M Pammi).