In this meta-analysis, VEGF -2578C > A gene polymorphism was not associated with the susceptibility of lung cancer in Caucasians (A allele: OR = 0.90, 95% CI: 0.74–1.11, P = 0.33; AA genotype: OR = 0.78, 95% CI: 0.55–1.12, P = 0.18; CC genotype: OR = 1.06, 95% CI: 0.76–1.47, P = 0.74; Table 2). Here, VEGFA is linked to lung carcinoma.