In this meta-analysis, VEGF -2578C > A A allele, and CC genotype were associated with the risk of lung cancer in Asians; however, the AA genotype was not (A allele: OR = 1.33, 95% CI: 1.15–1.55, P = 0.0002; AA genotype: OR = 1.45, 95% CI: 0.92–2.28, P = 0.11; CC genotype: OR = 0.68, 95% CI: 0.50–0.93, P = 0.01; Table 2). Here, VEGFA is linked to lung cancer.