Furthermore, hemizygous chromosomal deletions encompassing GLIPR1 have been reported in PCs from 9.4% of MM patients [39], and down-regulation of GLIPR1 was one of only 38 gene expression changes identified in PCs from patients with the MM-related malignancy light-chain amyloidosis, when compared with normal PCs [40]. This evidence concerns the gene GLIPR1 and Miyoshi myopathy.