Given that the GLIPR1 tumour suppressor gene was found to have significantly reduced expression levels in PCs from patients with amyloidosis [40] and to be deleted in 9.4% of MM patients [39], we hypothesised that the expression of GLIPR1 may also be down-regulated in the malignant PCs of MM patients. This evidence concerns the gene GLIPR1 and amyloidosis.