In the volcano plot, 44 proteins were detected with diminished abundance in Akt complex of MetS cells (green circles in Fig 5A), and also, 1 of the 4 proteins exclusively found in control (non-detectable levels in MetS) met the criteria of having at least 2 detected peptides, which adds for a final total of 45 proteins with diminished interaction with Akt in MetS cardiomyocytes (protein list in Table 2). Here, AKT1 is linked to metabolic syndrome.