Miyagawa et al[38] show that MALAT1 depletion or delocalization decreases the expression of 2′-5′-oligoadenylate synthetase like protein (OASL), interferon-induced protein 44 (IFI44), and serine peptidase inhibitor Kazal type 4 (SPINK4) in Hela cells; those genes or their family members are known to be involved in interferon and TGF-β associated lung fibrosis[39]. The gene discussed is SPINK4; the disease is pulmonary fibrosis.