CD40LG and dengue disease: Last, a significantly higher proportion of participants with anti-DENV IgM positive urine than negative urine had a blood urea nitrogen/creatinine ratio categorized as pre-renal (14.6% vs. 8.2%, WS = .06, CI95 0.01–0.13), a finding that may be seen in severe dengue patients with plasma leakage and/or gastrointestinal bleeding.