Consistently, the protein levels of LC3A/B‐II, p62 and Parkin in tumour tissues were increased by CTB, and Mdivi‐1 weakened these effects (Figure 8E, 8), suggesting that Drp1‐mediated mitochondrial fission played a vital role in the initiation and development of mitophagy. The gene discussed is PRKN; the disease is neoplasm.