No excess of any specific non-breast cancer was clearly identified in the biallelic CHEK2 PV carriers overall, though pancreatic cancer did appear to be more common among biallelic and CHEK2 c.1100del homozygous carriers (3.2% and 6.2%, respectively) as compared to monoallelic and CHEK2 c.1100del monoallelic carriers (0.2%; p = 0.0512 and 0.1%; p = 0.0277, respectively). This evidence concerns the gene CHEK2 and breast cancer.