The 2017 international consensus statement classifies tumors as “R” if the following criteria are fulfilled: no tumor contact with the SMV/PV or unilateral narrowing of the SMV/PV; no tumor contact with the SMA, CA, or CHA; a serum carbohydrate antigen (CA) 19-9 level of < 500 IU/ml; no regional lymph node metastasis; and performance status < 2 [16]. This evidence concerns the gene TCFL5 and neoplasm.