GNRH1 and Ovarian cyst: As already mentioned, one of the complications of using ovulation induction drugs is ovarian cysts that have been observed in the series of gonadotropin drugs, and approximately 20% of patients receiving GnRH during the follicular or luteal phase had developed ovarian cysts, so that the number of cysts in the follicular phase was higher than the luteal phase, and compared to the follicular phase cysts, the luteal phase cysts are more benign (59).