Pearson correlation analysis showed a significant negative correlation between VGLL3 and tumor homogeneity (r = −0.158, P = 2e-03, Fig. 3A), and a positive correlation with CD8+ T cells (r = 0.261, P = 3.72e-07, Fig. 3C), CD4+ T cells (r = 0.329, P = 1.15e-10, Fig. 3D), macrophages (r = 0.642, P = 2.75e-44, Fig. 3E) neutrophils (r = 0.365, P = 3.81e-13, Fig. 3F) and dendritic cells (r = 0.493, P = 4.16e-24, Fig. 3G), but not with B cells (P > 0.05, Fig. 3B). Here, CD8A is linked to neoplasm.