Nevertheless, the molecular functions of the top 10 biomarker candidates (Table 2) are linked to immune response (PIGR, C7, APCS), lipid metabolism (PLTP), and ECM (ADAMTSL2, COL6A1, COL6A2, LGALS3BP, CLU) and all relevant to NASH pathology. The gene discussed is CLU; the disease is metabolic dysfunction-associated steatohepatitis.