High LAT1 expression was associated with advanced pT stage (P = 0.0001), tumour grade (P = 0.0001), high neutrophil-to-lymphocyte ratio (NLR) (P = 0.0007), high LDH (P = 0.0017), and high IGFBP-5 score (P = 0.0001) among BC patients (Table 3). Here, IGFBP5 is linked to breast cancer.