In order to confirm the transcriptional role of NFкB (RelA) on the expression of FAT1 in GBM, we have cloned and characterized 4.0 kb FAT1-promoter pGL3F4 [− 3220 bp to + 848 bp, w.r.t. TSS (+ 1) having 17 NFкB (RelA) sites] and different FAT1 promoter-deletion constructs [pGL3F3 (3.1 kb), pGL3F2 (2.1 kb), pGL3F1 (1.0 kb), pGL3F1δ1 (0.86 kb), pGL3F1δ2 (0.25 kb)]. The gene discussed is RELA; the disease is glioblastoma.