Screening efforts for Sc should be focused on specific groups of people: those originating from or migrating through Africa; refugees; people aged 40 to 50 years; individuals with eosinophilia; or individuals with markers of poorly controlled HIV (i.e. CD4 counts < 200 cells/mm3, a detectable VL or no current ART). This evidence concerns the gene CD4 and Increased total eosinophil count.