Previous studies of the prognostic value of CRP for LVSD and HF in STEMI patients had significant limitations, such as retrospective case–control design, prior myocardial damage, LVEF assessed as continuous variable at a single early time point or not assessed at all, a single CRP measurement taken during initial hours of the hospitalization, low-sensitivity CRP assays, small heterogeneous populations, short-term observations, and different treatment strategies [16,18,21,22,23,24,25,26,27,28,29,30,31,32,33,34]. Here, CRP is linked to hydrops fetalis.