The recent data indicated that SAL itself affects a wide spectrum of mechanisms against OvCa biology, such as inhibition of the epithelial-mesenchymal transition (EMT) process (responsible for the development of metastatic disease), eradication of the CSC population (CD44+CD117+), and inhibition of the NF-ĸB signaling pathway (upregulation of proteins related to that pathway correspond with poor clinical prognosis in OvCa) [41,42,43,44]. Here, CD44 is linked to metastatic neoplasm.