GFAP and ischemia: In the 50 and 100 mg/kg YES-10/ischemia groups, the distribution pattern of GFAP immunoreactive astrocytes in the CA1 field was similar to that in the vehicle/ischemia group (Figure 4D,F), and their ROD was about 191% and 190%, respectively, of that in the vehicle/sham group (Figure 4I).