Literature evidence reported that PLTs from breast cancer patients contained significantly higher levels of VEGF, angiopoietin-1, and P-selectin compared to normal controls [27]; similarly, the concentrations of VEGF and platelet-derived growth factor (PDGF) were increased in colorectal cancer patients compared to controls [28], as well as in GBM patients [20]. The gene discussed is ANGPT1; the disease is glioblastoma.