Mutations in the collagen type III, alpha 1 gene (COL3A1), when associated with syndromic features such as facial dysmorphia, visible veins through translucent skin, and easy bruising, are common manifestations of EDS type IV, otherwise known as vascular EDS (vEDS) [55]. The gene discussed is COL3A1; the disease is Ehlers-Danlos syndrome, vascular type.