In addition, the adenoviral MUC1 vaccine ETBX-061, in combination with innate high-affinity Natural Killer (haNK) cell therapy and yeast-based vaccines, is used in a phase Ib/II trial to study the induction of T-cell responses in patients with advanced, unresectable, and untransplantable HCC. Here, MUC1 is linked to hepatocellular carcinoma.