In case of diseases, such as rheumatoid arthritis (RA), Crohn’s disease (CD), psoriasis, retinitis, multiple myeloma, diabetes, obesity, human immunodeficiency virus (HIV-AIDS)-mediated inflammations, and cognitive impairment, anti-TNF agents are the first drug of choice to lower the inflammation [47,48]. The gene discussed is TNF; the disease is rheumatoid arthritis.