In subsequent exploration, we found that δ‐catenin affected the translocation of β‐catenin, which further modulated the expression of its downstream apoptosis‐related protein Bcl2L1, cell cycle‐associated marker cyclin D1 as well as tumorigenic gene c‐myc and survivin, thereby facilitated proliferation and suppressed apoptosis in RCC. Here, BCL2L1 is linked to renal cell carcinoma.