Through genome‐wide functional enrichment analysis, we found that FOXP4‐AS1 may be involved in the following biological processes and pathways in PDAC: oxidative phosphorylation, TCA cycle, tumor immunity, classical tumor‐related pathways such as NF‐kB and JAK/STAT, cell proliferation, and adhesion. The gene discussed is NFKB1; the disease is neoplasm.