Results indicated a decrement of anaerobic metabolism both in DMD and BMD compared with controls; nevertheless, the decrement of Phosphoglycerate mutase (PYGM), Aldolase A (ALDOA), cytoplasmic Glycerol‐3‐phosphate dehydrogenase [NAD(+)] (GPD1), Triosephosphate isomerase (TPI1), Phosphoglycerate kinase (PGK1), Beta enolase (ENO3), and Pyruvate kinase M1/M2 (PKM2) was more profound in DMD patients. This evidence concerns the gene ALDOA and Duchenne muscular dystrophy.