Cytoskeletal/contractile proteins followed a similar trend being Filamin‐A (FLNA), Moesin (MSN), Embryonic myosin‐3 (MYH3), Perinatal myosin‐8 (MYH8), Non‐muscle myosin‐9 (MYH9), Embryonic muscle myosin light chain 4 (MYL4), Non‐muscle myosin light polypeptide 6 (MYL6), Spectrin beta chain (SPTB), Tubulin alpha‐1A chain (TUBA1A), Vimentin (VIM), and Alpha actin (ACTC1) increased in DMD compared either with BMD and controls. The gene discussed is SPTB; the disease is Duchenne muscular dystrophy.