ADIRF and Duchenne muscular dystrophy: Another characteristic specific of DMD is the change in muscle metabolism: the entire glycolytic/glycogen pathway and respiratory chain complex I activity are severely compromised with a signal for fatty acids accumulation (provided by a decrement of ACO2 and increment of APM2 and FASN) and for fatty acid beta‐oxidation (supported by PDH3 levels, dramatically decreased in DMD65).