It was reported that the inhibition of ASCT2 repressed reduced cancer cell growth and proliferation in LS174T cell line.3 Thus, it was assumed that ASCT2 might be a candidate target for the intervention of colon cancer, whereas the underlying role of ASCT2 in the pathogenesis of colorectal cancer remains not fully understood. Here, SLC1A5 is linked to malignant colon neoplasm.