SOD1 and Alzheimer disease: Oxidative and nitrosative stress statements are observed in the AD patients' brain.24, 25 As shown in Figure 3, oxidative stress (increased levels of ROS and MDA, decreased activities of SOD and GSH‐Px) and nitrosative stress (increased levels of NO and iNOS) were observed in Aβ‐treated SH‐SY5Y cells.