CEACAM5 and colorectal carcinoma: Importantly, multivariate Cox regression analysis showed that high stromal NNMT in CRC remained statistically significant predictor of DFS (HR, 1.415; 95%CI, 1.015‐1.972) and DSS (HR, 5.004; 95% CI, 2.301‐10.883) after adjusting for variables such as stage, grade, the number of resected lymph nodes, chemotherapy, serum CEA and serum CA199, as shown in Table 2.