Similarly, miR‐29c overexpression was reported to enhance the effect of gemcitabine by reducing autophagy in pancreatic cancer cells.45 MiR‐29c is proposed to interact with ubiquitin‐specific peptidase (USP)‐22, a deubiquitinating enzyme known to induce autophagy and promote pancreatic cancer cell survival. This evidence concerns the gene USP22 and familial pancreatic carcinoma.