To determine whether PTBP3 influences the malignancy of pancreatic cancer cells, we assessed whether the level of PTBP3 expression could alter proliferation by blocking the expression of PTBP3 in PANC‐1 cells and overexpressing PTBP3 in BxPC‐3 cells (Figure 2A). Here, PTBP3 is linked to familial pancreatic carcinoma.