Huang et al discovered that suppression of SCARA5 was also correlates with cellular invasion and overall progression in HCC.26 Furthermore, Xin‐Zhu Wen et al demonstrated that overexpression of SCARA5 could inhibit osteosarcoma proliferation and invasion though FAK signalling pathway.37 However, the function of SCARA5 in TC still remain to be fully elucidated. Here, PTK2 is linked to hepatocellular carcinoma.