(Nigrovic, Raychaudhuri & Thompson, 2018; Hersh & Prahalad, 2015; Viatte, Plant & Raychaudhuri, 2013) The genetic predisposition of JIA is attributable to HLA class II molecules (HLA-DRB1, HLA-DPB1), HLA class I molecules and non-HLA genes. Here, HLA-DRB1 is linked to juvenile idiopathic arthritis.