NRP1 and neoplasm: In our observation, B4GALNT1 overexpression did not affect cell proliferation in vitro, while multiple genes related to tumor cell proliferation-promoting, such as POSTN, IL13RA2, NRP1 were up-regulated, and EMILIN2, which is a proliferation-suppressing gene, was down-regulated notably in mRNA level (Fig. 2B, Table 3).