Now we aimed to investigate: i) the IgE seroprevalence to Anisakis allergens (Ani s 1 and Ani s 7 allergens, Anisakis crude extract allergens, allergens included in the ImmunoCAP kit) in workers that are professionally exposed to contact, air and food-borne in the fish processing industry, and ii) the potential risk factors for Anisakis-sensitization, including genetic susceptibility to anisakiasis by genotyping of human leukocytes alleles (HLA). Here, IGHE is linked to anisakiasis.