CXCR2 and cancer: Finally, in order to verify if the treatment with a CXCR1/CXCR2 allosteric inhibitor may modulate the cellular motility pathway triggered by nuclear localization of the transcription factors YAP and TAZ (inhibitors of the Hippo pathway controlling cell proliferation, cell migration and organs dimension, generally deregulated in cancer); the localization of these transcription factors (detected using the same antibody due to the very high homology) was investigated in the two cellular models.