DPY19L2 and Globozoospermia: Currently, recessive deletions and point mutations in two genes have been firmly identified as responsible for globozoospermia in humans: DPY19L2 (Harbuz et al. , 2011; Koscinski et al., 2011), accounting for more than 70% of all cases analysed (Ghedir et al., 2016; Ray et al., 2017), and SPATA16, representing less than 2% of the cases (Dam et al., 2007; ElInati et al., 2016).