It also showed increased binding by the respiratory chain regulator Gabpa (Ongwijitwat and Wong-Riley, 2005) (Nrf2 in the ENCODE database), which has been described as a regulator of normal hematopoietic and Chronic Myeloid Leukemia (CML) stem cells (Manukjan et al., 2016; Yang et al., 2013). This evidence concerns the gene GABPA and chronic myelogenous leukemia, BCR-ABL1 positive.