In addition, HD per se may stimulate an extra oxidative stress, furtherly attributed to antioxidants removed through dialyzer, and initiate neutrophil NADPH oxidase inflammative reaction to produce reactive oxygen species (Glorieux, Neirynck, Veys, & Vanholder, 2012; Modaresi, Nafar, & Sahraei, 2015). Here, FMO5 is linked to Huntington disease.