SPAG5 and ovarian cancer: Univariate analysis revealed that high SPAG5 expression (P = 0.001), tumor pathological grade (P = 0.031), lymph node metastasis (P = 0.001), distant metastasis (P = 0.001), and TNM staging (P = 0.001) were correlated with DFS in the 102 patients with ovarian cancer (Table 2).