CXCL8 and neoplasm: In terms of midkine's function in tumor progression, it is known that MK contributes to neoangiogenesis and tumor cell proliferation while inhibiting apoptosis.16, 19, 20 In addition, MK inhibits the interaction with T cells and contributes to the expression of pro‐inflammatory cytokines such as IL‐8 and TGF‐beta.