A similar negative relationship was also found between the persistence of AF and levels of hs-IL-6, although baseline levels of hs-IL-6 were highest in patients with paroxysmal AF (2.71, 2.96, 2.36, and 2.03 pg/mL for first-diagnosed, paroxysmal, persistent, and long-standing persistent AF, respectively,p < 0.001;Fig. 4[D-dimer only] andSupplementary Table S6). Here, IL6 is linked to atrial fibrillation.